The incidence of hypersensitivity reactions to non-steroidal anti-inflammatory drugs in patients with chronic urticaria
نویسندگان
چکیده
Background According to recent studies cutaneous manifestations to non-steroidal anti-inflammatory drugs (NSAID) may affect 0.3% of general population and the prevalence of aspirin hypersensitivity is as high as 27-35% in patients with chronic urticaria (CU). NSAID may be the cause of acute urticaria but in CU patients it usually exacerbates the disease by inhibition of the cyclooxygenase, which results in an increased synthesis and release of cysteinyl leukotrienes. The aim of our study was to investigate the incidence of reactions to NSAID as well as a possible relationship between NSAID hypersensitivity and the quality of life, disease activity and the response to treatment in CU patients.
منابع مشابه
علل و انواع بالینی واکنشهای دارویی ناخواستهی پوستی در بیماران مراجعهکننده به بیمارستان فرشچیان همدان در سالهای 87 و 88
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